ELIQUIS® (apixaban) is a prescription medication that plays a vital role in preventing and treating blood clots. It’s crucial to understand what Eliquis is used for, how it works, and its associated safety information to ensure its effective and safe use. This article provides a comprehensive overview of Eliquis, its uses, and important safety considerations.
Eliquis is a brand name for apixaban, belonging to a class of drugs known as anticoagulants, often referred to as blood thinners. These medications help to prevent the formation of blood clots by reducing the clotting ability of the blood. Understanding the specific conditions Eliquis is prescribed for is essential for patients and caregivers alike.
What Conditions Does Eliquis Treat? – Eliquis Uses
Eliquis is approved for several key medical conditions related to blood clot prevention and treatment. Here are the primary uses of Eliquis:
Reduce Stroke and Blood Clot Risk in Atrial Fibrillation (AFib)
Atrial fibrillation, often called AFib, is a type of irregular heartbeat not caused by heart valve problems. In AFib, the upper chambers of the heart beat irregularly and rapidly, which can lead to blood clots forming in the heart. These clots can travel to the brain and cause a stroke. Eliquis is prescribed to people with AFib to significantly reduce their risk of stroke and systemic embolism (blood clots that travel to other organs).
Treat Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE)
Deep vein thrombosis (DVT) is a condition where blood clots form in the deep veins, usually in the legs. Pulmonary embolism (PE) occurs when a blood clot travels to the lungs and blocks a blood vessel. Eliquis is used to treat both DVT and PE, helping to dissolve existing clots and prevent new ones from forming. This treatment is crucial in preventing serious complications associated with these conditions.
Prevent Blood Clots After Hip or Knee Replacement Surgery
Patients undergoing hip or knee replacement surgery are at an increased risk of developing blood clots in their legs and lungs due to reduced mobility and surgical trauma. Eliquis is prescribed to help prevent these blood clots from forming after hip or knee replacement surgery. This preventative measure is critical in ensuring a smoother recovery process and reducing the risk of post-surgical complications.
Important Safety Information and Warnings
While Eliquis is effective in preventing and treating blood clots, it’s important to be aware of the safety information and potential risks associated with its use.
Risk of Bleeding
As a blood thinner, Eliquis’s primary risk is bleeding. It can cause bleeding, which can be serious and, in rare cases, may be life-threatening. It’s crucial to be aware of the signs and symptoms of bleeding and to seek medical attention immediately if they occur.
Call your doctor or get medical help right away if you have any of these signs or symptoms of bleeding when taking ELIQUIS:
- Unexpected bleeding or bleeding that lasts a long time, such as unusual bleeding from the gums, nosebleeds that happen often, or menstrual or vaginal bleeding that is heavier than normal.
- Bleeding that is severe or you cannot control.
- Red, pink, or brown urine; red or black stools (looks like tar).
- Coughing up or vomiting blood or vomit that looks like coffee grounds.
- Unexpected pain, swelling, or joint pain.
- Headaches, or feeling dizzy or weak.
Alt text: Eliquis medication bottle held by a person’s hand, highlighting the prescription nature of the drug.
Your risk of bleeding may be higher if you take Eliquis with other medications that also increase bleeding risk, such as aspirin, NSAIDs (like ibuprofen or naproxen), warfarin, heparin, SSRIs, SNRIs, and other anticoagulants. Always inform your doctor about all medications, supplements, and over-the-counter drugs you are taking.
Stopping Eliquis
Do not stop taking ELIQUIS without talking to the doctor who prescribed it for you. Stopping ELIQUIS increases your risk of having a stroke, especially if you are taking it for atrial fibrillation. If you need to stop Eliquis before surgery or a medical procedure, your doctor will provide specific instructions on when to stop and when to restart it. They may also prescribe another medication to prevent blood clots while you are off Eliquis.
Spinal/Epidural Hematoma Risk
Patients taking Eliquis who receive spinal anesthesia or spinal puncture are at risk of developing a spinal or epidural hematoma (blood clot). This can lead to long-term or even permanent paralysis. The risk is increased if you have an epidural catheter, take NSAIDs or other anticoagulants, have a history of difficult spinal punctures, or have a history of spinal problems or surgery. Report any symptoms of spinal cord problems like tingling, numbness, or muscle weakness, especially in your legs and feet, to your doctor immediately.
Not for Artificial Heart Valves or APS
Eliquis is not for patients with artificial heart valves. It is also not recommended for people with antiphospholipid syndrome (APS), particularly those with positive triple antibody testing and a history of blood clots.
Before Taking Eliquis – Precautions
Before starting Eliquis, inform your doctor if you have:
- Kidney or liver problems
- Antiphospholipid syndrome (APS)
- Any other medical conditions
- A history of bleeding problems
- Pregnancy or are breastfeeding or plan to become pregnant or breastfeed. Discuss pregnancy planning and the risk of uterine bleeding with your doctor if you are a female who can become pregnant.
Alt text: Close-up view of white and yellow Eliquis tablets, showcasing the medication in pill form.
How to Take Eliquis
Take ELIQUIS exactly as prescribed by your doctor. It is typically taken twice daily, with or without food. Do not change your dose or stop taking it unless instructed by your doctor.
Dosage and Administration
Eliquis is available in 2.5-mg and 5-mg tablets. Your doctor will determine the appropriate dosage based on your condition and individual needs.
Missed Dose
If you miss a dose of Eliquis, take it as soon as you remember on the same day. Do not take more than one dose at the same time to make up for a missed dose.
Possible Side Effects of Eliquis
Besides the risk of bleeding, Eliquis can have other side effects.
Serious Side Effects (Bleeding, Allergic Reactions)
Serious side effects primarily include bleeding and allergic reactions. Allergic reactions may manifest as hives, rash, itching, swelling of the face or tongue, trouble breathing, wheezing, chest pain or tightness, dizziness, or fainting. Seek immediate medical help if you experience any of these allergic reaction symptoms.
When to Seek Medical Help
It is crucial to know when to seek medical help while taking Eliquis. In addition to the bleeding symptoms mentioned earlier, get medical attention right away if you experience any signs of a severe allergic reaction.
Conclusion
Eliquis is a vital medication for preventing strokes in atrial fibrillation, treating and preventing DVT and PE, and preventing blood clots after hip or knee replacement. Understanding what Eliquis is used for and its safety profile is crucial for patients. Always take Eliquis as prescribed by your healthcare provider and be vigilant about potential side effects, especially bleeding. If you have any concerns or questions about Eliquis, consult your doctor or pharmacist for personalized medical advice.
Disclaimer: This article provides general information and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment decisions.
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