What is Ketorolac? Uses, Benefits, and Risks

In the face of the opioid crisis, exploring alternatives to opioids for pain management is crucial. Clinicians are focusing on reducing opioid prescriptions, especially for high-risk individuals like young males, those with a history of abuse, and individuals with mental health issues.

Emergency rooms are seeing a decline in opioid prescriptions, but there’s still room for improvement. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), has shown effectiveness comparable to morphine for postoperative pain. This makes it a valuable option in emergency settings where opioids are often the go-to for moderate to severe pain.

When dealing with acute pain, a multimodal approach, combining different pain relief methods, can help minimize opioid use. An interprofessional team can also play a role in identifying patients who would benefit from alternative pain management options and coordinating the implementation of these strategies.

Understanding Ketorolac

So, What Is Ketorolac? Ketorolac is a powerful NSAID used to treat moderate to severe pain. It works by reducing hormones that cause pain and inflammation in the body. It’s available in various forms, including intravenous (IV), intramuscular (IM), and oral. While it’s effective, it’s important to understand its uses, benefits, and potential risks.

Benefits of Ketorolac

  • Effective Pain Relief: Ketorolac provides significant pain relief, often comparable to opioids, without the same risk of addiction.
  • Reduced Opioid Use: By offering an alternative, ketorolac helps reduce the reliance on opioids, minimizing the potential for misuse and dependence.
  • Versatile Administration: Available in IV, IM, and oral forms, ketorolac offers flexibility in how it can be administered based on the patient’s needs and the clinical setting.

Risks and Considerations

Despite its benefits, ketorolac carries a relatively high toxicity profile. Oral forms are typically recommended only after initial IV or IM doses.

  • Gastrointestinal Issues: Ketorolac can increase the risk of stomach ulcers, bleeding, and other gastrointestinal problems.
  • Kidney Problems: It can also affect kidney function, especially in individuals with pre-existing kidney conditions.
  • Cardiovascular Risks: Like other NSAIDs, ketorolac may increase the risk of heart attack or stroke.

Close collaboration among healthcare professionals is essential to minimize adverse outcomes and ensure that the right patients receive this medication.

The Role of Healthcare Providers

Healthcare providers play a crucial role in identifying individuals who could benefit from non-opioid pain medications like ketorolac, both in emergency departments and postoperatively.

Pharmacists are vital in this process due to their expertise in medication pharmacokinetics and proper dosing. They can ensure appropriate dosages, detect potential drug interactions, and help determine which patients are suitable for ketorolac.

Nurses, who spend significant time with patients, are responsible for administering ketorolac in its various forms and monitoring for toxicity. They also act as liaisons between the provider and the patient, reporting any adverse effects and advocating for patients who might be good candidates for ketorolac.

Nurses and pharmacists are responsible for reporting any concerns or issues to the rest of the healthcare team. Pharmacists must counsel patients on proper use, perform medication reconciliation, and contact the prescriber should they note any red flags, including potential drug interactions or adverse events.

Conclusion

Ketorolac is a valuable tool in the fight against opioid dependency, providing effective pain relief with careful consideration of its risks. By understanding what is ketorolac, its benefits, and potential side effects, and with a collaborative approach among healthcare providers, it can be used safely and effectively to manage pain and reduce the reliance on opioids.

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