Mounjaro, known generically as tirzepatide, is a medication primarily used to manage blood sugar levels in adults with type 2 diabetes, making it easier to live a healthier life, and you can find out more on WHAT.EDU.VN. This drug works by mimicking the effects of natural hormones to improve blood sugar control and can also aid in weight management. Interested in learning more about diabetes medications and how they work?
1. What Is Mounjaro and What Is It Used For?
Mounjaro is a brand-name medication containing tirzepatide, a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, primarily prescribed to enhance glycemic control in adults diagnosed with type 2 diabetes mellitus. According to research from Yale University School of Medicine in July 2023, tirzepatide has demonstrated superior efficacy in lowering HbA1c levels compared to other GLP-1 receptor agonists. It helps manage blood sugar levels in conjunction with diet and exercise. Beyond its primary function, Mounjaro has also been approved for chronic weight management in adults with obesity or who are overweight with at least one weight-related condition.
Alt text: Mounjaro injection pen used for managing blood sugar levels in type 2 diabetes and assisting in weight management.
2. How Does Mounjaro Work in the Body?
Mounjaro functions through a dual mechanism by activating both GIP and GLP-1 receptors. This dual action leads to several beneficial effects:
- Increased Insulin Release: Stimulates the pancreas to release insulin when blood sugar levels are high.
- Decreased Glucagon Secretion: Reduces the release of glucagon, a hormone that raises blood sugar levels.
- Slowed Gastric Emptying: Delays the emptying of the stomach, which helps reduce post-meal blood sugar spikes and promotes a feeling of fullness, aiding in weight loss.
This multifaceted approach contributes to improved blood sugar control and weight management.
3. Who Is Mounjaro Intended For?
Mounjaro is specifically intended for:
- Adults with type 2 diabetes mellitus to improve glycemic control, in addition to diet and exercise.
- Adults with obesity (BMI ≥ 30 kg/m²) or who are overweight (BMI ≥ 27 kg/m²) and have at least one weight-related condition (e.g., hypertension, dyslipidemia, type 2 diabetes).
It is not intended for individuals with type 1 diabetes or those without diabetes seeking only to lose weight.
4. What Are the Approved Dosages for Mounjaro?
The approved dosages for Mounjaro are:
- Starting Dose: 2.5 mg injected subcutaneously once weekly.
- Maintenance Dose: The dosage is gradually increased in 2.5 mg increments to reach a target dose of 5 mg, 10 mg, or 15 mg once weekly, based on individual patient needs and tolerability.
Dosage adjustments should be made under the guidance of a healthcare provider.
5. What Are the Potential Benefits of Using Mounjaro?
The potential benefits of using Mounjaro include:
- Significant reduction in HbA1c levels, indicating improved long-term blood sugar control.
- Effective weight loss, which can improve overall health and reduce the risk of weight-related complications.
- Potential reduction in the need for other diabetes medications.
- Improvements in cardiovascular risk factors, such as blood pressure and cholesterol levels.
6. What Are the Common Side Effects Associated With Mounjaro?
Common side effects associated with Mounjaro include:
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Abdominal pain
These side effects are typically mild to moderate and often diminish over time. If side effects persist or worsen, it is important to consult with a healthcare provider.
7. What Are the Serious Side Effects and Risks of Mounjaro?
Serious side effects and risks of Mounjaro include:
- Pancreatitis: Inflammation of the pancreas, which can cause severe abdominal pain.
- Hypoglycemia: Low blood sugar, especially when used with other diabetes medications like insulin or sulfonylureas.
- Kidney Problems: Worsening of kidney function in people with pre-existing kidney disease.
- Severe Allergic Reactions: Symptoms can include rash, itching, swelling, and difficulty breathing.
- Gallbladder Problems: Including gallstones and cholecystitis.
It is crucial to seek immediate medical attention if any serious side effects occur.
8. How Does Mounjaro Compare to Other Diabetes Medications?
Compared to other diabetes medications, Mounjaro (tirzepatide) has shown superior efficacy in clinical trials:
- GLP-1 Receptor Agonists: Mounjaro has demonstrated greater HbA1c reduction and weight loss compared to semaglutide and other GLP-1 receptor agonists. A study published in The Lancet in 2021 highlighted tirzepatide’s significant impact on glycemic control and weight reduction.
- Insulin: While insulin is effective at lowering blood sugar, Mounjaro offers the additional benefit of weight loss and a lower risk of hypoglycemia compared to insulin.
- Other Oral Medications: Medications like metformin and sulfonylureas may not be as effective in achieving significant HbA1c reduction or weight loss as Mounjaro.
9. Can Mounjaro Be Used for Weight Loss Even Without Diabetes?
Yes, Mounjaro can be prescribed off-label for weight loss in individuals without diabetes who meet specific criteria, such as having a BMI of 30 kg/m² or greater, or a BMI of 27 kg/m² or greater with at least one weight-related condition. However, it is important to consult with a healthcare provider to determine if Mounjaro is appropriate and to discuss the potential risks and benefits.
10. What Should I Discuss With My Doctor Before Starting Mounjaro?
Before starting Mounjaro, discuss the following with your doctor:
- Your medical history, including any existing conditions such as pancreatitis, kidney disease, or gallbladder problems.
- Any medications you are currently taking, including over-the-counter drugs and supplements.
- Any allergies you have to medications.
- If you are pregnant, planning to become pregnant, or breastfeeding.
- Any concerns you have about potential side effects.
11. How Is Mounjaro Administered?
Mounjaro is administered via subcutaneous injection once weekly. The injection can be given in the abdomen, thigh, or upper arm. It is important to follow your healthcare provider’s instructions carefully and to rotate injection sites to prevent skin irritation.
12. What Happens If I Miss a Dose of Mounjaro?
If you miss a dose of Mounjaro:
- Administer the missed dose as soon as possible within 4 days (96 hours) after the missed dose.
- If more than 4 days have passed, skip the missed dose and administer the next dose on the regularly scheduled day.
- Do not administer two doses within 3 days of each other.
13. Are There Any Specific Dietary Recommendations While Taking Mounjaro?
While taking Mounjaro, it is recommended to follow a balanced diet and engage in regular physical activity. Specific dietary recommendations may include:
- Eating a variety of nutrient-dense foods, including fruits, vegetables, whole grains, and lean proteins.
- Limiting intake of processed foods, sugary beverages, and high-fat foods.
- Controlling portion sizes to help manage blood sugar levels and promote weight loss.
Consulting with a registered dietitian or nutritionist can help create a personalized meal plan.
14. How Does Mounjaro Affect Blood Sugar Levels?
Mounjaro lowers blood sugar levels through multiple mechanisms:
- Stimulating insulin release from the pancreas when blood sugar levels are high.
- Reducing glucagon secretion, which prevents the liver from releasing excess glucose into the bloodstream.
- Slowing down gastric emptying, which reduces the rate at which glucose enters the bloodstream after meals.
These combined effects help to maintain stable blood sugar levels throughout the day.
15. What Are the Contraindications for Using Mounjaro?
Contraindications for using Mounjaro include:
- A personal or family history of medullary thyroid carcinoma (MTC).
- Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Known hypersensitivity to tirzepatide or any of the excipients in Mounjaro.
16. Can Mounjaro Be Used During Pregnancy or Breastfeeding?
Mounjaro is not recommended for use during pregnancy or breastfeeding. It is important to discuss alternative treatment options with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
17. What Drug Interactions Should I Be Aware Of?
Drug interactions to be aware of include:
- Insulin and Sulfonylureas: Mounjaro can increase the risk of hypoglycemia when used with insulin or sulfonylureas. Dosage adjustments of these medications may be necessary.
- Oral Medications: Mounjaro can slow gastric emptying, which may affect the absorption of oral medications. Your healthcare provider may need to monitor the effectiveness of these medications or adjust the timing of their administration.
18. How Should Mounjaro Be Stored?
Mounjaro should be stored in the refrigerator at 36°F to 46°F (2°C to 8°C). It should be protected from light and should not be frozen. If needed, Mounjaro can be stored at room temperature (up to 86°F or 30°C) for up to 21 days, but it should be discarded if not used within that time.
19. What Happens If I Overdose on Mounjaro?
If you overdose on Mounjaro, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, and hypoglycemia.
20. How Can I Monitor My Progress While Taking Mounjaro?
To monitor your progress while taking Mounjaro:
- Regularly check your blood sugar levels, especially if you have diabetes.
- Monitor your weight and track any changes.
- Attend regular follow-up appointments with your healthcare provider to assess your overall health and adjust your treatment plan as needed.
- Report any side effects or concerns to your healthcare provider.
21. What Are the Long-Term Effects of Mounjaro Use?
Long-term studies are ongoing to fully evaluate the long-term effects of Mounjaro use. However, current data suggest that Mounjaro can provide sustained improvements in blood sugar control and weight management over time.
22. How Does Mounjaro Impact Cardiovascular Health?
Mounjaro has shown potential benefits for cardiovascular health in clinical trials. It can improve cardiovascular risk factors such as blood pressure, cholesterol levels, and inflammation. Additional studies are needed to further evaluate the long-term cardiovascular effects of Mounjaro.
23. Can Mounjaro Be Used in Combination With Other Diabetes Treatments?
Yes, Mounjaro can be used in combination with other diabetes treatments, such as metformin, sulfonylureas, and insulin. However, it is important to work closely with your healthcare provider to adjust the dosages of these medications to avoid hypoglycemia.
24. What Should I Do If I Experience Severe Nausea While Taking Mounjaro?
If you experience severe nausea while taking Mounjaro:
- Eat smaller, more frequent meals.
- Avoid foods that are high in fat or very sweet.
- Stay hydrated by drinking plenty of fluids.
- Talk to your healthcare provider about anti-nausea medications if the nausea is persistent or severe.
25. Are There Any Lifestyle Changes That Can Enhance the Effects of Mounjaro?
Lifestyle changes that can enhance the effects of Mounjaro include:
- Adopting a healthy diet that is low in processed foods and high in fiber.
- Engaging in regular physical activity, such as walking, jogging, or swimming.
- Getting enough sleep and managing stress.
- Quitting smoking and limiting alcohol consumption.
Alt text: Healthy lifestyle choices, including balanced diet and regular exercise, can enhance the effects of Mounjaro in managing diabetes and weight.
26. How Can I Afford Mounjaro If It Is Expensive?
If Mounjaro is expensive, consider the following options:
- Check with the manufacturer for patient assistance programs or discount cards.
- Explore insurance options and compare different plans to find one that offers better coverage for Mounjaro.
- Talk to your healthcare provider about alternative medications that may be more affordable.
27. What Support Resources Are Available for People Taking Mounjaro?
Support resources available for people taking Mounjaro include:
- Diabetes education programs
- Support groups
- Online forums and communities
- Healthcare providers, including doctors, nurses, and dietitians
28. How Does Mounjaro Affect the Kidneys?
Mounjaro can affect the kidneys, particularly in individuals with pre-existing kidney disease. It is important to monitor kidney function while taking Mounjaro and to report any changes or concerns to your healthcare provider.
29. What Are the Signs and Symptoms of Pancreatitis?
Signs and symptoms of pancreatitis include:
- Severe abdominal pain that may radiate to the back
- Nausea
- Vomiting
- Fever
- Rapid pulse
If you experience these symptoms, seek immediate medical attention.
30. Can Mounjaro Cause Gallbladder Problems?
Yes, Mounjaro can increase the risk of gallbladder problems, such as gallstones and cholecystitis. Symptoms of gallbladder problems include:
- Sudden and intense pain in the upper right or center abdomen
- Pain that radiates to the right shoulder or back
- Nausea
- Vomiting
- Fever
- Jaundice (yellowing of the skin and eyes)
If you experience these symptoms, seek medical attention.
31. What Is the Mechanism of Action of Mounjaro on Weight Loss?
Mounjaro promotes weight loss through several mechanisms:
- Slowing down gastric emptying, which helps reduce appetite and increase feelings of fullness.
- Increasing insulin sensitivity, which can help the body use glucose more effectively.
- Reducing food intake by affecting appetite-regulating hormones.
32. How Effective Is Mounjaro Compared to Lifestyle Interventions for Weight Loss?
Mounjaro has been shown to be more effective than lifestyle interventions alone for weight loss. Clinical trials have demonstrated that Mounjaro can result in significant weight loss compared to diet and exercise alone.
33. Are There Any Psychological Effects Associated With Mounjaro?
Some individuals may experience psychological effects while taking Mounjaro, such as anxiety, depression, or changes in mood. It is important to report any psychological symptoms to your healthcare provider.
34. Can Mounjaro Be Used to Prevent Type 2 Diabetes?
Mounjaro is being investigated for its potential to prevent type 2 diabetes in high-risk individuals. Clinical trials are ongoing to determine if Mounjaro can reduce the risk of developing type 2 diabetes.
35. How Does Mounjaro Compare to Bariatric Surgery for Weight Loss?
Mounjaro is less invasive than bariatric surgery for weight loss. While bariatric surgery can result in more significant weight loss, it also carries greater risks and requires a longer recovery period. Mounjaro may be a suitable option for individuals who are not candidates for surgery or who prefer a less invasive approach.
36. What Is the Role of Genetics in Mounjaro’s Effectiveness?
Genetics may play a role in Mounjaro’s effectiveness. Individual genetic variations can influence how the body responds to Mounjaro and other medications. Further research is needed to fully understand the role of genetics in Mounjaro’s effectiveness.
37. Can Mounjaro Be Used in Adolescents With Type 2 Diabetes?
Mounjaro is not currently approved for use in adolescents with type 2 diabetes. Clinical trials are needed to evaluate the safety and effectiveness of Mounjaro in this population.
38. What Are the Ethical Considerations Surrounding the Use of Mounjaro for Weight Loss?
Ethical considerations surrounding the use of Mounjaro for weight loss include:
- The potential for misuse or overuse of the medication.
- The risk of unrealistic expectations or body image issues.
- The need to ensure equitable access to the medication for all individuals who could benefit from it.
39. How Does Mounjaro Affect Fertility?
The effects of Mounjaro on fertility are not well-established. It is important to discuss any concerns about fertility with your healthcare provider before starting Mounjaro.
40. What Are the Future Directions for Research on Mounjaro?
Future directions for research on Mounjaro include:
- Long-term studies to evaluate the long-term effects of Mounjaro use.
- Clinical trials to investigate the potential of Mounjaro to prevent type 2 diabetes.
- Studies to identify genetic factors that influence Mounjaro’s effectiveness.
- Research to evaluate the safety and effectiveness of Mounjaro in adolescents with type 2 diabetes.
Do you have questions about Mounjaro or other medications? Visit WHAT.EDU.VN, where you can ask questions and receive free answers from knowledgeable experts.
41. Understanding the Broader Impact of Mounjaro
Mounjaro’s impact extends beyond just managing diabetes and weight loss; it touches on various aspects of health and well-being. As more data emerges, it’s becoming clear that Mounjaro may offer benefits in areas such as cardiovascular health and overall metabolic function.
42. The Role of Mounjaro in Personalized Medicine
With the rise of personalized medicine, understanding how Mounjaro works on an individual level is crucial. Factors such as genetics, lifestyle, and other health conditions can influence how a person responds to Mounjaro. Tailoring treatment plans to individual needs can maximize the benefits and minimize potential risks.
43. Navigating the Emotional and Psychological Aspects of Treatment
Taking Mounjaro, like any medication, involves more than just the physical effects. Patients may experience a range of emotions, from hope and excitement to anxiety and frustration. Addressing these psychological aspects of treatment is essential for ensuring adherence and overall well-being.
44. Accessing Reliable Information and Support
With so much information available online, it can be challenging to discern fact from fiction. Reliable sources of information, such as healthcare professionals, reputable websites, and support groups, can help patients stay informed and make informed decisions about their health.
45. Empowering Patients Through Education
Education is a powerful tool for empowering patients to take control of their health. Understanding how Mounjaro works, potential side effects, and lifestyle modifications can help patients actively participate in their treatment and achieve better outcomes.
46. Mounjaro and the Future of Diabetes Care
Mounjaro represents a significant advancement in diabetes care, offering a novel approach to managing blood sugar levels and promoting weight loss. As research continues and new therapies emerge, the future of diabetes care looks brighter than ever.
47. Patient Testimonials: Real-Life Experiences with Mounjaro
Hearing from real patients who have taken Mounjaro can provide valuable insights and inspiration. These testimonials offer a glimpse into the day-to-day realities of living with diabetes or obesity and how Mounjaro has impacted their lives.
48. Common Myths and Misconceptions About Mounjaro
Despite its growing popularity, Mounjaro is still surrounded by myths and misconceptions. Debunking these myths is essential for ensuring that patients have accurate information and realistic expectations about the medication.
49. Expert Insights: Q&A with Healthcare Professionals
Gaining insights from healthcare professionals who have experience prescribing Mounjaro can be invaluable. These experts can provide guidance on dosage adjustments, side effect management, and other practical aspects of treatment.
50. The Importance of Holistic Care
While medications like Mounjaro can play a vital role in managing diabetes and obesity, they are just one piece of the puzzle. Holistic care, which addresses the physical, emotional, and social needs of patients, is essential for achieving long-term health and well-being.
FAQ About Mounjaro
| Question | Answer |
|---|---|
| Is Mounjaro a substitute for insulin? | No, Mounjaro is not a substitute for insulin, though it can be used in conjunction with insulin under medical supervision. |
| Can Mounjaro cure type 2 diabetes? | No, Mounjaro does not cure type 2 diabetes but helps manage blood sugar levels. |
| How quickly does Mounjaro start working? | Mounjaro starts working within a few weeks to lower blood sugar levels; noticeable weight loss may take longer. |
| What should I do if I accidentally inject too much Mounjaro? | Contact your healthcare provider immediately. Symptoms of overdose may include nausea, vomiting, and hypoglycemia. |
| Can I drink alcohol while taking Mounjaro? | It’s best to limit or avoid alcohol, as it can affect blood sugar levels and may increase side effects. Consult your healthcare provider for advice. |
| Is Mounjaro safe for elderly patients? | Mounjaro can be used in elderly patients, but caution is advised due to potential increased risk of side effects. |
| How does Mounjaro interact with birth control pills? | Mounjaro can slow gastric emptying, which may affect the absorption of oral birth control pills. Consider using a non-oral contraceptive method. |
| Can Mounjaro cause hair loss? | Hair loss is not a common side effect of Mounjaro but has been reported in rare cases. |
| Does Mounjaro require a special diet? | A balanced diet is recommended to enhance the effects of Mounjaro. |
| Can Mounjaro be used long-term? | Yes, Mounjaro can be used long-term to manage type 2 diabetes and weight. |
| What alternative medications are similar to Mounjaro? | Similar medications include other GLP-1 receptor agonists like semaglutide and dulaglutide, which also help lower blood sugar and promote weight loss. |
| How often should I see my doctor while taking Mounjaro? | Regular check-ups, typically every 1-3 months, are important to monitor your health and adjust your treatment plan as needed. |
| What are the psychological benefits of Mounjaro? | Psychological benefits may include improved mood and self-esteem due to better health management and weight loss. |
| Does Mounjaro affect cholesterol levels? | Yes, Mounjaro has been shown to improve cholesterol levels, contributing to cardiovascular health. |
| What should I do if I plan to have surgery while on Mounjaro? | Inform your surgeon and healthcare provider about Mounjaro use, as it may affect anesthesia and recovery. |
| How effective is Mounjaro for weight loss compared to other drugs? | Mounjaro has demonstrated superior weight loss compared to many other weight loss drugs, offering significant reductions in body weight. |
| Can Mounjaro cause changes in vision? | While not common, changes in vision should be reported to your doctor, as they could indicate other underlying issues. |
| What are the benefits of combining Mounjaro with exercise? | Combining Mounjaro with exercise enhances weight loss, improves blood sugar control, and boosts overall fitness. |
| Can Mounjaro improve my energy levels? | Improved blood sugar control and weight loss can lead to increased energy levels. |
| What should I expect during the first week of taking Mounjaro? | Common experiences include mild nausea, changes in appetite, and adjustments in blood sugar levels. |
| How does Mounjaro compare to Trulicity? | Mounjaro often shows superior results in both HbA1c reduction and weight loss compared to Trulicity due to its dual-action mechanism on GIP and GLP-1 receptors. |
| What is the best time of day to take Mounjaro? | Mounjaro is typically taken once a week and can be administered at any time of day, as long as it is consistent from week to week. |
| How should I dispose of used Mounjaro pens? | Dispose of used Mounjaro pens in a sharps container following local guidelines to prevent injuries and ensure proper disposal. |
| Can Mounjaro affect my menstrual cycle? | Changes in menstrual cycles are not commonly reported with Mounjaro but should be discussed with a healthcare provider if they occur. |
| What foods should I avoid while taking Mounjaro? | Avoid high-sugar and high-fat foods to enhance the effects of Mounjaro and manage blood sugar levels. |
| What happens if Mounjaro is not refrigerated properly? | If Mounjaro is not refrigerated properly, it may lose its effectiveness. Follow storage guidelines carefully to ensure the medication remains potent. |
| Can Mounjaro cause dehydration? | Yes, side effects like nausea, vomiting, and diarrhea can lead to dehydration. Drink plenty of fluids to stay hydrated. |
| What are the benefits of taking Mounjaro for PCOS? | Mounjaro may help manage insulin resistance and weight, improving some symptoms of PCOS; consult with a healthcare provider for personalized advice. |
| Can Mounjaro affect my mood? | While not common, some individuals may experience mood changes. Report any significant changes in mood to your healthcare provider. |
| What should I do if I develop a rash after taking Mounjaro? | Discontinue use and contact your healthcare provider immediately, as it may indicate an allergic reaction. |
| How does Mounjaro affect blood pressure? | Mounjaro can help lower blood pressure, especially in individuals with hypertension. |
| What should I know about traveling with Mounjaro? | Keep Mounjaro in its original packaging, store it properly, and bring a copy of your prescription. |
| Can Mounjaro affect liver function? | Monitor liver function if you have liver problems, as Mounjaro may affect liver enzymes. |
| What are the benefits of taking Mounjaro for fatty liver disease? | Mounjaro can help reduce liver fat and improve liver function in individuals with fatty liver disease. |
| Can Mounjaro cause fatigue? | While improved blood sugar control may increase energy, some individuals might initially experience fatigue. |
| What should I do if I have severe abdominal pain while on Mounjaro? | Seek immediate medical attention, as severe abdominal pain can indicate pancreatitis or gallbladder problems. |
| How does Mounjaro affect kidney disease? | Monitor kidney function closely, as Mounjaro may worsen kidney disease. Consult your healthcare provider for personalized advice. |
| What are the benefits of Mounjaro for individuals with heart failure? | While not specifically indicated for heart failure, improved blood sugar control and weight loss can benefit individuals with heart failure; consult your healthcare provider. |
| Can Mounjaro improve sleep quality? | Improved blood sugar control and weight loss can indirectly improve sleep quality. |
| What are the benefits of taking Mounjaro for gout? | Mounjaro may help manage insulin resistance, which can indirectly benefit individuals with gout; consult your healthcare provider. |
| Can Mounjaro affect my ability to drive? | Monitor blood sugar levels closely and be cautious when driving, as hypoglycemia can impair your ability to drive safely. |
| What are the benefits of taking Mounjaro for mental health? | Improved blood sugar control and weight loss can positively impact mental health, reducing symptoms of depression and anxiety. |
| Can Mounjaro affect my immune system? | Mounjaro is not known to significantly affect the immune system but should be monitored in individuals with compromised immunity. |
| What are the benefits of taking Mounjaro for nerve pain? | Mounjaro may indirectly help manage nerve pain by improving blood sugar control in individuals with diabetes-related neuropathy. |
| Can Mounjaro improve my athletic performance? | Improved blood sugar control and weight loss can enhance athletic performance but should be monitored by a healthcare provider. |
| What are the long-term benefits of taking Mounjaro for Alzheimer’s? | Research on the effects of Mounjaro on Alzheimer’s is ongoing, but improved blood sugar control and insulin resistance may offer potential benefits. |
| Can Mounjaro affect my skin health? | Improved blood sugar control can positively impact skin health, reducing the risk of skin infections and improving wound healing. |
Mounjaro offers significant benefits for managing type 2 diabetes and weight, but it’s essential to be well-informed and consult with healthcare professionals for personalized advice.
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Remember, the information provided here is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.
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